Edema
Definition
An abnormal accumulation of fluid in the interstitial tissue is known as edema.
Fluid
collections in the  body cavities are
known as effusion
•     
Hydrothorax or pleural effusion
•     
Hydropericardium or pericardial effusion
•     
Hydroperitoneum
or ascites 
•     
Normally
fluid movement between vascular space and interstitial tissue is controlled by 
•     
Vascular
Hydrostatic pressure
•     
governed by blood flow
•     
 in pressure moves fluid out of the vessel 
•     
Plasma
colloid osmotic pressure
•     
plasma proteins maintains osm.pressure
•     
 in osm. Pressure maintains 
fluid within the vascular space 
1.    
Causes of Edema
INCREASED HYDROSTATIC PRESSURE
INCREASED HYDROSTATIC PRESSURE
•     
Impaired venous return e.g. Congestive heart failure; cirrhosis
•     
Venous obstruction or compression
2.
REDUCED PLASMA OSMOTIC PRESSURE (HYPOPROTEINEMIA)
•     
Liver cirrhosis; Malnutrition    
3.  LYMPHATIC OBSTRUCTION
•     
  inflammation; Neoplasm
4.
INFLAMMATION
•     
    Acute inflammation
•     
    Chronic inflammation
   
5. SODIUM
RETENTION
•     
Renal failure
•     
Increased tubular reabsorption 
Type of
edema
•     
Trasudate
–   
 ultrafiltrate of blood plasma and contains
little protein
–   
Conditions
with increased hydrostatic pressure or decreased oncotic pressure
–   
Specific
gravity  <1.012 
•     
Exudate
–   
edema
fluid rich in protein
–   
Conditions
associated--Inflammation
–   
specific
gravity > 1.020.
 
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