Edema
Definition
An abnormal accumulation of fluid in the interstitial tissue is known as edema.
Fluid
collections in the body cavities are
known as effusion
•
Hydrothorax or pleural effusion
•
Hydropericardium or pericardial effusion
•
Hydroperitoneum
or ascites
•
Normally
fluid movement between vascular space and interstitial tissue is controlled by
•
Vascular
Hydrostatic pressure
•
governed by blood flow
•
in pressure moves fluid out of the vessel
•
Plasma
colloid osmotic pressure
•
plasma proteins maintains osm.pressure
•
in osm. Pressure maintains
fluid within the vascular space
1.
Causes of Edema
INCREASED HYDROSTATIC PRESSURE
INCREASED HYDROSTATIC PRESSURE
•
Impaired venous return e.g. Congestive heart failure; cirrhosis
•
Venous obstruction or compression
2.
REDUCED PLASMA OSMOTIC PRESSURE (HYPOPROTEINEMIA)
•
Liver cirrhosis; Malnutrition
3. LYMPHATIC OBSTRUCTION
•
inflammation; Neoplasm
4.
INFLAMMATION
•
Acute inflammation
•
Chronic inflammation
5. SODIUM
RETENTION
•
Renal failure
•
Increased tubular reabsorption
Type of
edema
•
Trasudate
–
ultrafiltrate of blood plasma and contains
little protein
–
Conditions
with increased hydrostatic pressure or decreased oncotic pressure
–
Specific
gravity <1.012
•
Exudate
–
edema
fluid rich in protein
–
Conditions
associated--Inflammation
–
specific
gravity > 1.020.
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